I noticed----NO I AM STILL CHASING TONE IN ALL ITS GLORY--- wasnt an option
For me - personally - I have a signature sound at home and that's my DSL40C, 55Hz Reaper, and Weber attenuator.
It really doesn't matter which of my 3 guitars I play, as they all sound very similar, which is something I strived for - familiarity in both feel and tone. Each guitar has a unique purpose - i.e. the double neck for 12 string passages or stage presence, the S-G tuned E-flat and the Les Paul generally tuned standard or used as an E-flat backup.
When in my band character, his tonal needs are totally different.
The hood and mask wearing "Sledge," as he has been affectionately named by bandmates, needs gain bordering on absolute madness, something not even a TS-9 has yielded. The Line-6, 75 watt head has delivered. Actual speaker presence is an absolute necessity, meaning he can't record direct.
The bassist uses a somewhat "Geezer-ish" mid range tone, and the guitar actually has a very pronounced bass signature in its tone.
This isn't at all new, as I recall working in Buck Owens Studio in Bakersfield and going through room fills of gear trying to find a tone the producer/engineer wanted.
As far as volume/tone controls on the instrument are concerned, I run pretty much full up all the time and everything is EQ'd at the amp and the console. A 3 band EQ cannot even come close to my tonal needs.
Now, working in the country music genre, I recall frequently adjusting guitar tone and volume to suit the producer/engineer and going as far as painting marks on the guitar with white out or tape - the #1 reason I put pointers on all my guitars.
But in this genre, the tonal spectrum is more complex in that some individual frequencies are pulled way down and others are pushed way up - to such a degree that the EQ sliders sometimes resemble a staircase, so its a very different world altogether...