For me the sound of the ´80s was what Gary Moore, Vivian Campbell and Matthias Jabs used (some others as well) - a JCM800 with a BOSS DS1 in front and of course on (almost)full volume, Matthias used a 1979 Superlead but that was very close to the JCM800.
Vivian used the DiMarzio Superdistortion on Holy Diver, Matthias used a Bill Lawrence in his black Strat and the stock Gibson with his Explorer, Gary Moore used some EMGs in the mid 80s.
I think it is more the player than the pickup.
You can make some serious sounds using a T-Top and a BOSS DS1 plugged into a JCM800.
Back in those days I used a Rockinger Strat with a DiMarzio X2N pickup into a JCM800 or Laney AOR (and my Hoyer V of course - a Seymour Duncan 59 in the bridge position).
I have the JB in my Charvel San Dimas (MiJ) it has a solid tone but a bit muddy in the midrange, not as clear as a Duncan 59 or the T-Top.
The Duncan has more bottom end and the T-Top has more bite.
Life is good,
Robin